Typhoid IgG/IgM Rapid Test Kit

Typhoid IgG/IgM Rapid Test Kit

The Typhoid IgG/IgM Rapid Test Kit is a rapid chromatographic immunoassay for the qualitative detection of antibodies (IgG and IgM) to Typhoid virus in Whole Blood /Serum / Plasma to aid in the diagnosis of Typhoid viral infection.

Intended Use

The Typhoid IgG/IgMĀ Rapid Test KitĀ is a rapid chromatographic immunoassay for the qualitativeĀ detection of antibodies (IgG and IgM) to Typhoid virus in Whole Blood /Serum / Plasma to aid inĀ the diagnosis of Typhoid viral infection.

Summary

Typhoid fever is a bacterial disease, caused by Salmonella typhi. It is transmitted through theĀ ingestion of food or drink contaminated by the faeces or urine of infected people. SymptomsĀ usually develop 1ā€“3 weeks after exposure, and may be mild or severe. They include high fever,malaise, headache, constipation or diarrhoea, rose-coloured spots on the chest, and enlargedĀ spleen and liver. Healthy carrier state may follow acute illness. Typhoid IgG/IgMĀ Rapid Test KitĀ isĀ a simple, visual qualitative test that detects Typhoid antibodies in human WholeĀ Blood/serum/plasma. The test is based on immunochromatography and can give a result withinĀ 15 minutes.

Principle

The Typhoid IgG/IgMĀ Rapid Test KitĀ is a qualitative membrane strip based immunoassay for theĀ detection of Typhoid antibodies (IgG and IgM) in Whole Blood /Serum / Plasma. The test deviceĀ consists of: 1) a burgundy colored conjugate pad containing Typhoid recombinant envelopeĀ antigens conjugated with Colloid gold (Typhoid conjugates) and rabbit IgG-gold conjugates,2) aĀ nitrocellulose membrane strip containing two test bands (T1 and T2 bands) and a control bandĀ (C band). The T1 band is pre-coated with the antibody for the detection of IgG anti-Typhoid, T2Ā band is coated with antibody for the detection of IgM anti-Typhoid, and the C band is pre-coatedĀ with goat anti rabbit IgG. When an adequate volume of test specimen is dispensed into theĀ sample well of the test cassette, the specimen migrates by capillary action across the cassette.Ā IgM anti-Typhoid, if present in the specimen, will bind to the Typhoid conjugates. TheĀ immunocomplex is then captured by the reagent pre-coated on the T2 band, forming a burgundyĀ colored T2 band, indicating a Typhoid IgM positive test result and suggesting a fresh infection.Ā IgG anti-Typhoid if present in the specimen will bind to the Typhoid conjugates. TheĀ immunocomplex is then captured by the reagent coated on the T1 band, forming a burgundyĀ Ā colored T1 band, indicating a Typhoid IgG positive test result and suggesting a recent or repeatĀ infection. Absence of any T bands (T1 and T2) suggests a negative result. The test contains anĀ internal control (C band) which should exhibit a burgundy colored band of the immunocomplexĀ of goat anti rabbit IgG/rabbit IgG-gold conjugate regardless of the color development on any of
the T bands. Otherwise, the test result is invalid and the specimen must be retested with anotherĀ device.
Brand

REAGEN

Model

RNS92127

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